December 06, 2012

Bowel Cancer Breath Test is 76% accurate

Scientists say they have developed a breath-test that can accurately tell if a person has bowel cancer.

The test, which looks for exhaled chemicals linked to tumour activity, was able to identify a majority of patients with the disease.

The British Journal of Surgery reported an overall accuracy of 76%.

However, another scientist said it was unlikely a fully functioning and reliable breath-test would be available soon for the general public.

Scientists are working on breath-tests for a host of other diseases, including several types of cancer, TB and diabetes.

If diagnosed and treated early, the chances of stopping cancer can be good, but there is often little or no outward sign of the disease until it has progressed significantly.



The current screening test for bowel cancer looks for signs of blood in the faeces, but only a small proportion of those who test positive actually have colorectal cancer, which means unnecessary and invasive further testing for many people.

The breath-test technology relies on the idea that the biology of tumours can lead to the production of specific "volatile organic compounds", combinations of chemicals unlikely in a healthy person.

The team from a hospital in Bari, southern Italy, compared the breath of 37 patients known to have bowel cancer with that of 41 "controls" who were thought to be healthy.

The initial test identified the cancer patients with 85% accuracy, and although, when combined with a follow-up test, the overall result fell to 76%, the researchers were upbeat about its potential.


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