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July 14, 2010

Life Extension Foundation Funds Granulocyte Anti-Cancer Therapy for $800000

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Dr. Zheng Cui, of the Wake Forest University School of Medicine, developed a colony of mice with super-charged granulocytes and those mice could withstand virulent cancer.

When Dr. Cui administered healthy, potent granulocytes to mice with cancer that couldn’t be treated by other known therapies, he cured them. Dr. Cui also found that a similar cancer-killing activity is present in the granulocytes of some healthy humans. Based on these findings, Dr. Cui proposed a novel therapeutic concept for treating human cancers. In his proposal, healthy humans who possess a high level of cancer-killing activity can be identified by a unique laboratory assay and be used as granulocyte donors. The donor granulocytes can be specifically collected by an established procedure and be infused into cancer patients to treat the diseases. This therapy worked exceptionally well in preclinical studies. Dr. Cui who showed in laboratory experiments that immune cells from some people can be almost 50 times more effective in fighting cancer than in others. What that means is that these super-charged granulocytes can be harvested from healthy young donors and infused into cancer patients with curative intent.

No one stepped forward to fund a clinical study to see if this new therapy could cure cancer

* The Life Extension Foundation learned that this potential cancer cure was not being funded, it immediately made a $200,000 grant to fund the study at the South Florida Bone Marrow/Stem Cell Transplant Institute

* In January of this year, Dr. Maharaj, Director of the South Florida Bone Marrow/Stem Cell Transplant Institute, notified the Life Extension Foundation that progress was being slowed because expected funding sources had dried up. Life Extension responded with another grant of $600,000 to further advance what could be a cure for cancer


Phase 1 and 2 of the clinical trials are now projected to be done in June 2012


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