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June 14, 2010

Tranexamic acid Could reduce Bleeding deaths by 15% or 100,000 lives per year

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Up to 100,000 lives could be saved every year if a known drug (tranexamic acid TXA), were given to seriously bleeding trauma patients.
In countries like India and China it could save about 12,000 lives each year. The Lancet shows that tranexamic acid (TXA), which helps blood to clot, could lower the risk of dying by 15%. TXA costs about US$4.50 per gram; it is easily administered and does not need to be refrigerated.

Each year 600,000 injured patients bleed to death worldwide. World Health Organisation figures show that nearly six million people die each year from injuries, which accounts for 10% of the world's deaths.


Most of those injury deaths occur in developing countries, where deaths from road traffic crashes and homicide have been steadily increasing. Almost half of those deaths are caused by bleeding. The patients were injected with 1g of TXA within a few hours of being injured, followed by another 1g in a drip over the next eight hours, or a matching placebo.

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