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July 24, 2006

New scanning mass spectrometry nanoprobe created for better cell analysis

Nano probe may open new window into cell behavior at physorg and eurekalert. Georgia Tech researchers have created a nanoscale probe, the Scanning Mass Spectrometry (SMS) probe, that can capture both the biochemical makeup and topography of complex biological objects in their normal environment -- opening the door for discovery of new biomarkers and improved gene studies, leading to better disease diagnosis and drug design on the cellular level.



Georgia Tech's SMS Probe gently pulls biomolecules precisely at a specific point on the cell/tissue surface, ionizes these biomolecules and produces "dry" ions suitable for analysis and then transports those ions to the mass spectrometer.

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