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November 13, 2005

Preview of Molecular nanotech issues: Ordering DNA sequences

YOU might think it would be difficult for a terrorist to obtain genes from the smallpox virus, or a similarly vicious pathogen. Well, it's not. Armed with a fake email address, a would-be bioterrorist could probably order the building blocks of a deadly biological weapon online, and receive them by post within weeks.

That's the sobering reality uncovered by a New Scientist investigation into the bioterror risks posed by the booming business of gene synthesis. Dozens of biotech firms now offer to synthesise complete genes from the chemical components of DNA (See "A dollar a base pair"). Yet some are carrying out next to no checks on what they are being asked to make, or by whom. It raises the frightening prospect of terrorists mail-ordering genes for key bioweapon agents such as smallpox, and using them to engineer new and deadly pathogens.

These loose ordering procedures are even more of a problem when combined with the recent publication of the 1918 flu virus which was critized by Ray Kurzwell and Bill Joy

The combination of loose ordering procedures and loose informational procedures is a bad combination.

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